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To investigate whether an interaction between diltiazem and

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response to Simvastatin ( Zocor ) in diltiazem-treated patients. Enhanced cholesterol

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reduction by Simvastatin ( Zocor )

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in diltiazem-treated patients.AIMS. The cholesterol reduction for the 19 patients on diltiazem was 33.3%

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compared with 24.7% in the remaining 116

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patients (median difference 8.6%, 95% CI 1.1-12.2%, P. From the clinic records we extracted and recorded absolute

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and percentage cholesterol responses to the starting dose of Simvastatin ( Zocor ) and coprescription

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of diltiazem. One hundred and thirty-five patients attending the Denys hypertension clinic who started consecutively on Simvastatin

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( Zocor ) for primary or secondary prevention of Coronary Heart Disease (CHD) during the 2 years Stephie, 1996-May 1998 were surveyed.